Vabysmo (faricimab-svoa) is a brand-name drug that’s prescribed for certain eye conditions in adults. Vabysmo comes as an injection into the eye. The dosage can vary, depending on what condition the drug is used to treat.

Specifically, Vabysmo is approved to treat wet age-related macular degeneration (AMD) and diabetic macular edema in adults.

Vabysmo is a biologic and belongs to a drug class called dual vascular endothelial growth factor (VEGF) and angiopoietin-2 (Ang-2) inhibitors. Vabysmo isn’t available in a biosimilar version.

Keep reading for specific information about the dosage of Vabysmo, including its strength and how to use the medication. For a comprehensive look at Vabysmo, see this article.

Note: This article describes typical dosages for Vabysmo provided by the drug’s manufacturer. However, your doctor will prescribe the Vabysmo dosage that’s right for you.

Read on for more details about Vabysmo’s dosage for its approved uses.

Vabysmo form

Vabysmo solution comes as an injection into your eye. Your healthcare professional will give you your injection.

Vabysmo strength

Vabysmo comes in one strength: 120 milligrams (mg) per milliliter (mL). Each single-dose vial contains 6 mg in 0.05 mL of solution.

Typical dosages

The following information describes dosages that are commonly used or recommended. However, your doctor will prescribe the dosage that’s right for you.

Dosage for Neovascular (Wet) Age-Related Macular Degeneration

The recommended dosage of Vabysmo for wet age-related macular degeneration (AMD) is 6 mg given as an injection into the eye by your healthcare professional. You’ll usually receive one dose every 4 weeks for the first four doses.

Your doctor will check your eyes using optical coherence tomography (OCT) and a visual acuity test 8 weeks after your last dose. They’ll repeat these tests 4 weeks later to determine your dosing regimen. Then you’ll usually receive a 6-mg dose as one of the following schedules:

  • once every 16 weeks
  • once every 12 weeks
  • once every 8 weeks

In some cases, your doctor may recommend that you receive your injection once every 4 weeks. However, clinical trials of Vabysmo showed that one dose every 4 weeks wasn’t more effective for wet AMD than one dose every 8 weeks.

Dosage for Diabetic Macular Edema

Vabysmo has two dosage regimens for diabetic macular edema. You’ll receive either:

  • 6 mg once every 4 weeks for four doses, followed by and eye exam and OCT. Your doctor may recommend that you receive your next injection once every 8, 12, or 16 weeks based on the results of your eye exams.
  • 6 mg once every 4 weeks for the first six doses. Then you’ll receive 6 mg once every 8 weeks.

In some cases, your doctor may recommend that you receive your injection once every 4 weeks. However, clinical trials of Vabysmo showed that one dose every 4 weeks wasn’t more effective for diabetic macular edema than one dose every 8 weeks.

Long-term treatment

Vabysmo is meant to be used as a long-term treatment. If you and your doctor determine that Vabysmo is safe and effective for you, you’ll likely take it long term.

The Vabysmo dosage your doctor prescribes will depend on the type and severity of the condition you’re using Vabysmo to treat.

Other medical conditions you have can also affect your Vabysmo dosage.

Vabysmo is given as an injection into your eye by a healthcare professional. You’ll receive your injection at your doctor’s office. You can learn more about how to prepare for your appointment and what to expect after your injection on the manufacturers website.

If you miss an appointment for your Vabysmo injection, reschedule as soon as possible. Typically, you can receive your injection within 7 days of your scheduled dose.

To help make sure that you don’t miss an appointment, try using a medication reminder. This can include setting an alarm or putting a note where you’ll see it, such as on your bathroom mirror or bedside table. You could also download a reminder app on your phone.

The dosages in this article are typical dosages provided by the drug manufacturer. If your doctor recommends Vabysmo for you, they’ll prescribe the dosage that’s right for you.

If you have questions about the dosage of Vabysmo that’s best for you, talk with your doctor.

Besides learning about dosage, you may want other information about Vabysmo. These additional articles might be helpful:

  • More about Vabysmo. For information about other aspects of Vabysmo, refer to this article.
  • Details about your condition. For details about your condition, see our eye health hub.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.