Kisunla (donanemab-azbt) is a brand-name drug that’s prescribed for Alzheimer’s disease in adults. Kisunla comes as a solution for intravenous infusion that’s given by a healthcare professional.
Kisunla is a biologic and belongs to a drug class called beta amyloid-directed antibodies. Kisunla isn’t available in a biosimilar version.
Keep reading for specific information about the dosage of Kisunla, including its strength and how to use the medication. For a comprehensive look at Kisunla, see this article.
This article describes typical dosages for Kisunla provided by the drug’s manufacturer. However, your doctor will prescribe the Kisunla dosage that’s right for you.
Note: As a person’s condition progresses, they may need help reading or understanding information regarding their treatment plan. This article contains details that may help caregivers learn more about Kisunla.
The information below describes Kisunla’s typical dosages and other details about the drug.
Kisunla form
Kisunla comes as a liquid in a single-dose vial. The solution is given as an intravenous (IV) infusion by a healthcare professional. You’ll receive the IV infusion in a hospital, infusion center, or clinic.
Kisunla strength
Kisunla comes in one strength of 350 milligrams (mg) per 20 milliliters (mL) of solution (17.5 mg/mL).
Typical dosages
Typically, your doctor will start by prescribing you a low dosage. Then, they’ll adjust it over time to reach the amount that’s right for you. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect.
The following information describes dosages that are commonly prescribed in adults.Your doctor will determine the best dosage to fit your needs.
Dosage for Alzheimer’s disease
Doctors may prescribe Kisunla to treat Alzheimer’s disease.
If your doctor prescribes Kisunla for Alzheimer’s disease, your starting dose will likely be 700 mg. Typically, you’ll receive this dose as an infusion every 4 weeks. After your first three doses, your doctor may recommend increasing your dosage to 1,400 mg every 4 weeks. This is the typical recommended dosage of Kisunla for people with Alzheimer’s disease. This is also the maximum dose of Kisunla that’s recommended.
The table below shows the typical dosage schedule, including the starting dosage and maintenance dosage. Your doctor will choose a maintenance dose that suits your needs.
| Treatment month | Recommended Kisunla dosage |
|---|---|
| months 1 to 3 | 700 mg every 4 weeks |
| month 4 and beyond | 1,400 mg every 4 weeks |
For more information about your specific dosage, talk with your doctor.
How to use Kisunla
Your doctor or another healthcare professional will give you the IV infusion of Kisunla. They’ll prepare the liquid solution for infusion by diluting the Kisunla vial before your infusion. You’ll likely go to your doctor’s office, infusion center, or a hospital to receive your infusion. The infusion takes about 30 minutes. You’ll also typically need to remain at the infusion center for at least 30 minutes after the infusion.
General guidance
If you have questions about how to use Kisunla, talk with your doctor or pharmacist.
Long-term treatment
Kisunla is meant to be used as a long-term treatment. If you and your doctor determine that Kisunla is safe and effective for you, you’ll likely use it long term.
Before you start using Kisunla, your doctor will discuss your treatment plan with you.
ACCESSIBLE DRUG LABELS AND CONTAINERSSome pharmacies offer labels with large print, braille, or a code you scan with a smartphone to convert text to speech. If your local pharmacy doesn’t have these options, your doctor or pharmacist might be able to recommend a pharmacy that does.
If you’re having trouble opening medication bottles, ask your pharmacist about putting Kisunla in an easy-open container. They also may recommend tools that can make it easier to open bottles.
Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.