Generation Of Multi-layered Structures For Biomedical Applications Using A Novel Tri-needle Co-axial Device And Electrohydrodynamic Flow

Main Category: Medical Devices
Article Date: 23 Jul 2008 - 3:00 PDT

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In this report we describe the design, construction and operation of a novel device, which consists of three co-axial capillaries and invaluable for the rapid advancement of healthcare engineering.

The device can transport different combinations of fluids and suspensions simultaneously and under the influence of an electric field bubble or spray or spin the output generating double-layered bubbles, porous encapsulated threads and multi-layered nanocapsules by a single step process.

The rapid generation of such structures immensely advances modern drug delivery and tissue engineering strategies, for example by facilitating multi-stage controlled release from fine multi-layered capsules/threaded scaffolds, by enhancing the use of drug-encapsulated microbubbles in ultrasound-mediated surgery.

Journal of the Royal Society Interface

Journal of the Royal Society Interface is the Society's cross-disciplinary publication promoting research at the interface between the physical and life sciences. It offers rapidity, visibility and high-quality peer review and is ranked fifth in JCR's multidisciplinary category. The journal also incorporates Interface Focus, a peer-reviewed, themed supplement, each issue of which concentrates on a specific cross-disciplinary subject.

http://www.publishing.royalsociety.org/interface